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Barton ER, DeMeo J, Lei H

Upon binding of both O 2 and NADPH to CuSAE, NADPH is oxidized to NADP + by donating electrons to the CuSAE, through which O 2 acquires electrons and forms O 2 - radicals

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I called it More Than a Performance Enhancer. Because theres if you just look at where its distributed in the body, almost every cell in every tissue has the creatine system

Furthermore, copper deficiency impairs the activity of certain Cu/Zn-oxides, which may lead to increased accumulation of ROS and oxidative stress, which further promotes inflammation and atherosclerosis (104)

Zeng Y-Q, He J-T, Hu B-Y, Li W, Deng J, Lin Q-L, et al