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Among the NK cells subset, CD56 dim PC-phospholipase C bright cells are associated with cytotoxic function, whereas CD56 bright PC-phospholipase C low/- cells exhibit immunoregulatory properties (133) ( Figure 3 )
Liu J, Liu F, Cai W, Jia C, Bai Y, He Y, et al
347 A separate study found that adults aged 20-40 years given 20 mg PQQ daily for 12 weeks had a significant improvement in processing speed and executive speed after eight weeks compared with placebo
doi: 10.1146/annurev-physiol-012110-142233 58 JinP.BianY.WangK.CongG.YanR.ShaY
These studies showed that through the targeted elimination of mutated mtDNA, a beneficial shift in heteroplasmy and improvement in the biochemical deficit can be achieved [62,63,64,65,66,67]
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