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2015 Aug 6;15:84.

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doi: 10.1016/j.biopha.2014.06.001

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Hepatocyte growth factor enhances vascular endothelial growth factor-induced angiogenesis in vitro and in vivo

The development of several PAMs that are highly selective for mGlu 2 and have properties suitable for in vivo testing has enabled the identification of mGlu 2 as the major group II mGlu receptor subtype that could be pursued as a therapeutic strategy for reducing drug taking and seeking across a variety of classes of drugs