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2 Effects of metformin on PCOS PCOS is a common disorder of hormonal and metabolic imbalance, characterized by hyperandrogenism, dysfunctional ovulation, and polyfollicular ovaries and accompanied by metabolic abnormalities, such as insulin resistance (IR) and obesity (Zhao et al., 2023), affecting women during their reproductive years, with potential long-term cardiovascular, metabolic, and reproductive health outcomes (Zhu et al., 2022

Wang M, Zhang Y, Feng J, Gu T, Dong Q, Yang X, et al

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Ans) Nausea is a common side effect of the medicine but not at severity

Studies have suggested that high-dose vitamin C IV drips, at the proper concentration, can result in destruction of cancer cells without harming healthy cells

Access this article Similar content being viewed by others Abbreviations -GCL: -glutamate cysteine ligase GGT: -glutamyl transferase BSO: L-buthionine-(S, R)-sulfoximine GPx: glutathione peroxidase GSH and GSSG: reduced and oxidized glutathione, respectively MAPK: mitogen-activated protein kinase miR: microRNA Nrf2: NF-E2-related factor 2 ROS: reactive oxygen species REFERENCES Scir, A., Cianfruglia, L., Minnelli, C., Bartolini, D., Torquato, P., Principato, G., Galli, F., and Armeni, T