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Although many efforts have been made in this field, the chemical synthesis of peptides has been a relatively unexplored area

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High dietary intakes methionine (56 g/day) on the other hand have been shown to raise plasma levels of homocysteine, despite adequate intakes of B vitamins [3133]

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In humans mitochondrial inheritance is through the oocyte, although there is some evidence supporting extremely rare transmission of some mitochrondria through sperm, resulting in heteroplasmy, or mixed populations of mitochondria in an individual

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Abbreviations: ALK: Anaplastic lymphoma kinase

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Temporary dryness or mild irritation in rare cases

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