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in fact, stereoisomers of an anesthetic can have very different narcotic potency, even though their oil/gas partition coefficients are similar (Cameron 2006)
J Alzheimer's Dis 36, 197209

Cell 153:12391251 Chhiba KD, Kuang FL (2024) Advancing toward a unified eosinophil signature from transcriptional profiling
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doi: 10.4103/ijmr.IJMR_1144_16 138 JauhariABaranovSVSuofuYKimJSinghTYablonskaSet al