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significance of counteraction of vascular and multiorgan failure of occlusion/occlusion-like syndrome in cytoprotection/ 16: Sikiric P, Boban Blagaic A, Strbe S, Beketic Oreskovic L, Oreskovic I, Sikiric S, Staresinic M, Sever M, Kokot A, Jurjevic I, Matek D, Coric L, Krezic I, Tvrdeic A, Luetic K, Batelja Vuletic L, Pavic P, Mestrovic T, Sjekavica I, Skrtic A, Seiwerth S

doi: 10.1111/j.1365-2796.2010.02318.x

10.1097/DBP.0b013e31817dc447 22 BhakarA

Metformin may suppress the key ferroptosis driver ACSL4 (which promotes toxic lipid biosynthesis) through AMPK pathway activation or reduce iron-dependent cellular damage by modulating iron metabolism-related proteins (e.g., downregulating transferrin receptor)

It's a common belief that because of its antioxidant properties, glutathione supplements could benefit all cancer patients

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