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Aside from limiting the formation of aggregates, the polarity of these spacers also alter the interaction of the ADCs with permeability glycoprotein (Pgp) which is a major cause of multi-drug resistance (MDR) by the tumor cells (28)

BioDrugs (2008) This citation provides a foundation for understanding the role of amylin in metabolic regulation, which is central to the discussion of Cagrilintides mechanism of action

OS is involved in MS through both central and peripheral mechanisms (169)

[DOI] [PMC free article] [PubMed] [Google Scholar] 99.Wilcken B

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