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Besides, in the nucleus DJ-1 sequesters the death-associated protein, Daxx, preventing its translocation to the cytosol to activate ASK-1 mediated cells death [155]

As regards cell biochemical markers, in the uroli-thiasis model, erastin significantly reduced the antioxidant capacity of HK-2 cells, leading to an increase in the levels of mitochondrial membrane potential, lipid peroxidation and ROS

[DOI] [PMC free article] [PubMed] [Google Scholar] 49.Rowland LM, Spieker EA, Francis A, Barker PB, Carpenter WT, Buchanan RW