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Description

AJR Am J Roentgenol 2005;184:1340-1346

Clinuvel Pharmaceuticals intended to offer it as a cosmetic, but abandoned this pursuit in the 2000s due to regulatory restrictions and concerns about the promotion of suntanning

Rubio-Ruiz B, Serrn-Aguilera L, Hurtado-Guerrero R, Conejo-Garca A

They are lipotoxic in that they can accumulate in cells and tissues that are not equipped to metabolize or store them adequately with a profound influence on cell viability and function, and they can affect tissue metabolism directly or after reaction with other tissue components to give further lipid mediators

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