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A 5% NAC solution is administered orally at an initial loading dose of 140 mg/kg, followed by 70 mg/kg every six hours for at least seven doses [120]

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In addition to ethanol and acetaldehyde, other compounds activate ALDH2, although the exact mechanisms remain incompletely understood

Elevated 4-HNE is found in the cerebral tissues of individuals with Alzheimer's after autopsy (Yoo et al

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