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doi: 10.1016/B978-0-12-801284-0.00004-X

Nucleic Acids Res 46 , 1139611404 (2018)

In practice, conversion requires multiple enzymes (MTR, MTRR, SHMT, MTHFR, MTHFS) all working properly, plus adequate B12, B6, riboflavin, and glutathione

Magtanong L, Ko P-J, To M, Cao JY, Forcina GC, Tarangelo A, et al

To provide protection against ROS, repair oxidative damage and maintain a reducing intracellular environment, (developing) red cells are equipped with a variety of antioxidants, including superoxide dismutase 1 and 2, catalase, glutathione peroxidase 1, peroxiredoxin I and II, and glutathione (GSH)-synthesizing enzymes (van Zwieten et al., 2014

STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors