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How Dihexa Works (Proposed and Partly Retracted) The proposed mechanism is that Dihexa potentiates hepatocyte growth factor (HGF) signaling at the c-Met (MET) receptor, downstream of PI3K-AKT, driving dendritic spine formation and synaptogenesis

[DOI] [PMC free article] [PubMed] [Google Scholar] 90.He Y., Yue Y., Zheng X., Zhang K., Chen S., Du Z

[DOI] [PMC free article] [PubMed] [Google Scholar] 53.Tong H., Zhang X., Meng X., Lu L., Mai D., Qu S

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The mechanism underlying Dihexas effects appears to involve its action as an HGF/c-Met receptor agonist

Emerging research is also exploring their potential effects on the brain, including whether they can help reduce cravings for drugs, alcohol and nicotine