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Dannheim, Abigail R

Ataxia with oculomotor apraxia type1 (AOA1): novel and recurrent aprataxin mutations, coenzyme Q10 analyses, and clinical findings in Italian patients

In the co-factor or coenzyme forms , the upper ligand is either a methyl ( methylcobalamin, MeCbl ) or a 5-deoxyadenosyl ( adenosylcobalamin, AdoCbl ) group

10.1016/j.tem.2019.09.005 [DOI] [PubMed] [Google Scholar] Kobayashi, T., & Cohen, P

Additionally, mitochondrial permeability transition pore (mPTP) opening causes Cyt C release, exacerbating ATP depletion and shifting cell death toward pyroptosis [54]

Dosage of B12 injections Injections may be given every month until B12 levels have returned to normal