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(Liu et al., 2022) conducted a longitudinal study involving Chinese community residents aged 65 years, revealing that HHcy escalates the risk of MetS, particularly among individuals with abdominal obesity

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Tolerance development : Effects diminish over time, requiring higher doses

However, for B12, if any part of that complex digestive process is compromised especially the intrinsic factor or the absorption sites in the intestine then a significant portion of the B12 from a tablet might never reach your bloodstream