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The effect of lipopolysaccharide from uropathogenic Escherichia coli on the immune system, testis tissue, and spermatozoa of balb/c mice

Israel Chaikoff, an observation now known as the Wolff-Chaikoff effect ( 3 and T 4 , this effect acts to block the excessive amounts of iodide in the body from generating large amounts of thyroid hormone ( However, the Wolff-Chaikoff effect is transient, usually lasting only one to two days, after which an escape occurs where regular synthesis of thyroid hormones resumes ( Notably, excess amounts of daily iodide ranging from 30 mg to 2 g are typically well tolerated in individuals with normal thyroid glands

Jpn Pharmacol Ther 2018;46:561580.

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10.1016/j.meegid.2016.09.004 201 UrakamiY.OkudaM.MasudaS.SaitoH.InuiK