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The action of PTH in the DCT results in increased levels of calbindin-D 28K allowing for more reabsorbed calcium to be transported to the basolateral membrane for efflux to the blood

PARthanatos: DNA damage-driven energy collapse and inflammatory storm PARthanatos is a unique programmed cell death pathway characterized by hyperactivation of poly ADP-ribose polymerase 1 (PARP-1), leading to depletion of nicotinamide adenine dinucleotide (NAD+) and ATP, and triggering mitochondrial release and nuclear translocation of apoptosis-inducing factor (AIF) [63]

doi:10.1016/j.molmed.2017.08.001 Massudi H, Grant R, Braidy N, Guest J, Farnsworth B, Guillemin GJ

The decreased NAA levels within corticalbasal ganglia networks indicate neuronal death and mitochondrial metabolic impairment in PD

NIH Training Grant Fellow: Morgan Dragan Morgan Dragan is a PhD candidate in Dr