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In this study, ERO1A was down-regulated, whereas the expression of SEC63 was up-regulated at the protein level in response to riboflavin deficiency, suggesting that riboflavin deficiency impairs the oxidative folding and subsequent secretion of proteins in HepG2 cells

Extensive human trials are being conducted to investigate the therapeutic efficacy and outcomes of IGF-1-related therapy

doi: 10.1016/j.biomaterials.2020.119755

Cell Metab 22(3):48598 [DOI] [PMC free article] [PubMed] [Google Scholar] 88.Cant C, Menzies KJ, Auwerx J

Prolonged expression of p16, like p21, can induce senescencelike arrest in cancer cells (Uhrbom et al ., 1997)

Multi-dose vial management Most peptide vials contain multiple doses