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It is a component of the glutathione-ascorbate cycle, a system that reduces poisonous hydrogen peroxide

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doi: 10.4049/jimmunol.0900365 196 RajaramMVBrooksMNMorrisJDTorrellesJBAzadAKSchlesingerLS

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Both YAP1 and ZEB1 are potential predictors of sensitivity to ferroptosis inducers GTP cyclohydrolase (GCH1)