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2023 Sep 11;64(6):453-459

Metabolomic signatures of drug response phenotypes for ketamine and esketamine in subjects with refractory major depressive disorder: new mechanistic insights for rapid acting antidepressants

You may have heard of it, possibly tried it, and then like most, dismissed it as another snake oil

Five patients discontinued treatment due to lack of efficacy or unwillingness to continue

Eysiaks W, Lilly K, Dilisao F, Toth PP, Bieber LL (1988) The journal of biological chemistry quantitation of the effect of L-Carnitine on the levels of acid-soluble short-chain acyl-CoA and CoASH in rat heart and liver mitochondria*

Additionally, some studies have evaluated outcomes over 12 weeks or longer, though individual responses may vary
