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Cross-referencing DEGs with FRGs curated from FerrDb, a database of validated ferroptosis regulators [29], revealed that 21 ferroptosis driver genes were downregulated in Dmp1-Cre

This relationship can allow for dosage adjustments or alternative medications if one seems like a better fit for the patient

(2) although iron chelators and antioxidants have been used to modulate ferroptosis, their therapeutic efficacy remains inadequate, limiting their clinical utility

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The 5-end primers additionally encoded a near-Kozak consensus sequence to ensure efficient translation