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Moreover, many intermediary metabolites generated from glycolytic and oxidative phosphorylation serve as cofactors or substrates of epigenetic enzymes involved in post-translational modification and gene expression

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Current research findings suggest that it may promote fat loss, enhance lipid metabolism, and improve overall metabolic health with a favorable safety profile

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Higher NAD enhances SIRT1 activity, promoting fat oxidation and mitochondrial remodeling via PGC-1 pathwaysmechanisms consistent with improved endurance and recovery potential (Cant et al., Cell Metabolism

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