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Phase I and Phase II detoxification are two stages of the bodys natural process for breaking down and eliminating potentially harmful substances, including drugs, toxins, and metabolic waste products

XK assisted in data analysis and interpretation, performed all statistical analysis, and edited and approved the manuscript
Histone lactylation: from tumor lactate metabolism to epigenetic regulation

Patients with a history of chronic hepatitis B or hepatitis C virus infection, HIV/AIDS, TB, uncontrolled T2DM, SARS-CoV2 infection within 6 months, and a history of alcohol abuse within 6 months were excluded

Research has shown that miR-1185-1 and SIRT1 have contrasting impacts on the formation of CSCs in CRC, such that SIRT1 decreases the levels of miR-1185-1, leading to an elevation in CD24 expression and augmentation in CSCs [72]
2015;8:Cd010497
