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Continuous, topologically guided protein crystallization controls bacterial surface layer self-assembly

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10.1126/science.281.5384.1851 28 BrunengraberH.RoeC

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In posterior segments of the gut (e.g., the cecum and proximal large intestine), gut microbes directly cleave the CN bond of carnitine to release TMA, which subsequently enters the liver through the portal circulation, is converted to TMAO by hepatic flavin monooxygenases (FMOs) [242, 243], and eventually enters the blood circulation [244]