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MYCN overexpression transforms normal neuroectodermal cells into neuroblasts by stimulating the expression of growth-promoting genes 10,11,12,13,14

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Some studies suggest Nrf2 activation promotes KC hyperproliferation initially observed in HaCaT cells and later confirmed in a mouse model

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Disruptions in gut microbiota composition and SCFA production are increasingly associated with a range of pediatric health issues, including obesity, allergic disorders, inflammatory bowel disease (IBD), and neurodevelopmental disorders

10.2174/13816128113190990411 [DOI] [PubMed] [Google Scholar] Sikiric P., Seiwerth S., Rucman R., Turkovic B., Rokotov D