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Sex-specific mechanisms in vascular aging: exploring cellular and molecular pathways in the pathogenesis of age-related cardiovascular and cerebrovascular diseases

Construct design, expression and purification of GluK3 D759G receptors for structural studies The native signal peptide of GluK3 was substituted with that of GluK2 and sub-cloned into the pEGBacMam vector for baculovirus-based expression in mammalian cells in order to improve surface expression

Next, we successfully achieved overexpression of CBS and GCLC in DDX3X-deficient cells (Fig

The body has a natural system to remove these reactive O2 species

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