glutathione tcm Taohong Siwu Decoction modulates metabolism to suppress hepatocyte ferroptosis and demonstrates anti-fibrotic effects in the liver Yiqi Huoxue Lishui–based Optimized New

Preclinical research evidence Animal Experiments Obese mouse model: After subcutaneous injection of AOD 9604 (250 g/kg) daily for 8 weeks, the body weight of obese mice decreased by 12%, the subcutaneous fat mass decreased by 25%, and the weight of epididymal adipose tissue decreased significantly

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Cannarella R, Condorelli RA, Mongio LM, Barbagallo F, Calogero AE, La Vignera S

The vehicle alone represented 0.1% DMSO in medium or PBS

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(2011), who showed that TrkA activation via NGF induces the nuclear translocation of Nrf2 and subsequently induces the transcription of ARE-containing genes, including ngfb , in PC12 cells