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This observation is in line with (a) decreased plasma GSH levels in women who underwent surgical menopause (Kaur et al., 2017), and (b) decreased serum tGSH levels in post- relative to pre-menopausal women (Ramrez-Expsito et al., 2014)

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Collectively, the animal studies of moderate brain injuries suggest that such injuries cause a release of signaling molecules which results in a disruption of the ionic balance across the cell membrane immediately after the injury event