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Kongsted P, Borch TH, Ellebaek E, Iversen TZ, Andersen R, Met , et al

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HMGB 1 mediates hyperglycaemia-induced cardiomyocyte apoptosis via ERK/Ets-1 signalling pathway

doi: 10.1056/NEJM199701163360306

[6] In vitro data referenced within the study indicated that AOD-9604 may promote differentiation of adipose-derived mesenchymal stem cells toward osteogenic lineages and may stimulate production of proteoglycans and type II collagen in isolated bovine chondrocyte cultures, both critical components of the extracellular matrix underpinning cartilage structural integrity
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