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Given that various chemical substances have been identified as neurotransmitters/neuromodulators in mammals, eliciting long-distance ionic responses that effectively mediate neurotransmission, identification of more systematic signaling molecules in the future would offer new insights into the complex systemic defense signaling in plants

Jerman, L

doi: 10.1164/rccm.201010-1596OC

Although no data from randomized clinical trials (RCT) currently exists on the use of cannabinoids to treat non-motor symptoms in PD, RCTs that have evaluated the impact of cannabinoids on quality of life in Parkinson's disease patients have reported either an improvement or no benefit [66]

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