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Although ultracentrifugation has been acccepted as the gold standard for exosome isolation, several issues remain to be addressed, such as expensive equipment, long processing time (4 6 hours), limited recovery rate, and purity problems caused by co-precipitation of other extracellular vesicles and protein complexes (127)
2019;157:507521.e4
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Thyroid cancer Thyroid carcinoma is the most prevalent endocrine malignancy, with steadily increasing incidence, partly due to enhanced diagnostic techniques detecting smaller tumors, showing higher rates in women than in men (Prete et al
