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However, its C-terminal end can be cleaved by carboxypeptidase A, and removal of the last leucine residue (L585) weakens receptor binding, reducing its half-life from 20 days to 3.5 days in humans

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In particular, cluster 3 was characterized by a continuous increase in ECM protein expression, which involved in the upregulation of collagen and fibronectin expression (e.g., Fn1, Fbln1, Col4a2, Col18a1) after the BLM administration (Fig

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Combining them allows for a more comprehensive GH modulation, supporting both immediate and sustained benefits across fat metabolism, recovery, and overall vitality

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