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Bolognese, Paolo

To ensure understanding will be evaluated (and the model will be generalizable), we assembled and carefully curated a dataset comprising approximately 13,000 small molecule pKa values

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Compared to healthy controls, MS patients show significantly downregulated expression of TET2 in peripheral blood mononuclear cells (PBMCs), correlating with abnormal methylation patterns in the promoter regions of TET2 and DNMT1 (134)
