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however, it was significantly lower than that observed in the plasma

[DOI] [PMC free article] [PubMed] [Google Scholar] 165.Burga RA et al

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The design of protein separation involves the differences in chemical, structural, and functional properties between the target protein and other proteins in the crude mixture, which include size, shape, charge, isoelectric point, charge distribution, hydrophobicity, solubility, density, ligand-binding affinity, metal binding, reversible association, posttranslational modifications, and specific sequences or structures