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In vitro mechanistic studies also showed that the lead compound C1-27 acts as a slow-turnover substrate, though the significance of this mechanism is currently unclear

Karlsen R, et al

Discussion Gsr / mice were found to be highly susceptible to C

Therefore, decreasing glucose absorption rate mediated by AC contributes to its antidiabetic effect

doi:10.1136/bmj.r454

Science 350:13911396 Yurimoto H, Oku M, Sakai Y (2011) Yeast methylotrophy: metabolism, gene regulation and peroxisome homeostasis
