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Nery FG, Weber WA, Blom TJ, Welge J, Patino LR, Strawn JR, et al

CREATEing Community for Colorectal Surgeon-Scientists

Availability of data and materials Data will be made available at a reasonable request
Problem or Solution: The Strange Story of Glucagon

GPX4 oxidizes GSH into glutathione (GSSG) and reduces toxic L-OOH to non-toxic L-OH, which controls the spread of lipid peroxide and maintains the stability of cytomembrane (Xu et al

It has been shown that alveolar epithelial lining fluid of patients with ARDS is deficient in total GSH compared to normal subjects (107), and neutrophil-mediated oxidants release leads to GSH deficiency and lung cell injury (107)
