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Referencias y estudios recientes Kazeminasab, F., Miraghajani, M., Ahmadinejad, S., Sharafifard, F., Carteri, R

The rationale for adding it to tirzepatide is that calorie restriction and GI side effects from GLP-1 medications can reduce B12 absorption, potentially leading to deficiency over time

doi: 10.1016/S0021-9258(18)47692-2 106 KnorrSSinnMGaletskiyDWilliamsRMWangCMullerNet al

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To assess statistical differences between groups, univariate comparisons were conducted using two-sample t-tests with confirmation by Wilcoxon rank-sum tests, given the small sample size