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Treatment of inherited disorders of vitamin B12 absorption, transport, uptake and metabolism typically includes regular, high-dose intramuscular injections of vitamin B12 in the form of cyanocobalamin (standard in the United States), hydroxycobalamin (standard in Europe), or increasingly methylcobalamin

2) Therapeutic limitations and innovations: Current ferroptosis inhibitors (Fer-1, Lip-1, and DFO) suffer from poor aqueous solubility, short half-lives, and off-target effects (e.g., DFO-induced iron deficiency anemia)

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After brief aspiration to check for blood vessel puncture, inject slowly over 5-10 seconds

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