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These results suggest that modulating the redox environment and ROS levels through MCJ silencing or ROS scavenging with MitoQ can significantly impact ccRCC progression and metastasis, potentially by affecting the secretion of legumain

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doi: 10.1038/srep15548

4 , 52 , 54 , 55 Details of the analytical methods for the determination of several markers (glutathione, cysteine, ascorbic acid, uric acid, malondialdehyde, protein carbonyls, 3-nitrotyrosine) have been described by Weber et al