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Reduced GSH reacts with free radicals to form oxidized glutathione (GSSG), which can be catalyzed by the enzyme glutathione peroxidase (GPx) or occur independently

In the neonatal form of GCE, symptoms appear in the first few days of life and include lethargy, hypotonia, myoclonic jerks, and often death

Pediatrics 120, 11831215

Hydrogen Sulfide Treatment Mitigates Renal Allograft Ischemia-Reperfusion Injury During Cold Storage and Improves Early Transplant Kidney Function and Survival Following Allogeneic Renal Transplantation

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The molecule was formed by connecting GSH with cholesterol through a short link [two ethylene glycol units: -O(C 2 H 4 OC 2 H 4 )O-]