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The BM consists of members of the laminin family, nidogens, heparan sulfate proteoglycans, perlecan, and collagens 91

19 Early studies: There were studies in the 1950s and the1960s that showed that oral vitamin B 12 could be absorbed by patients with pernicious anemia and could lead to resolution of the anemia

B12 plays an important role in the recycling of N5-methyl THF (the storage form of folate) to THF, the form of folate that serves as a coenzyme for numerous metabolic reactions involving amino acids and nucleic acids

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Glucose Metabolism : Uncontrolled T1D leads to increased hepatic glucose output