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Biomed Pharmacother 106:285291

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Side effects have only occurred after regular ingestion of excessive amounts of fruits and included restlessness and insomnia [256]

The end products of purine metabolism, uric acid, a potent antioxidant, have been reported to be found in decreased levels in MDD 71,72,73 , while lower cerebro-spinal fluid (CSF) levels of hypoxanthine and xanthine, the two metabolites preceding uric acid, have previously been linked with depression 74

Week ending 2/1/2020 to 12/5/2020. National Center for Health Statistics
