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Loren Pickart human plasma Cu Copper Complex Blue-green solution is normal Mechanism of Action How GHK-Cu Works Copper delivery, collagen synthesis activation, and 4,000+ gene modulation COPPER Primary Copper Ion Delivery Cu Complexation & Delivery Delivers bioavailable Cu to tissue Activates copper-dependent enzymes Supports lysyl oxidase for collagen crosslinking COLLAGEN Key Collagen & ECM Synthesis TGF- / Fibroblast Activation Upregulates collagen I and III synthesis Increases fibronectin and laminin production Activates dermal fibroblast proliferation GENOMIC 4,000+ Gene Expression Modulation Broad Transcriptomic Effects Activates tissue repair gene networks Downregulates inflammation pathway genes Modulates Wnt and TGF- signaling Key finding: GHK-Cu plasma levels decline from ~200 ng/mL in young adults to ~80 ng/mL by age 60 a 60% reduction

doi: 10.1172/jci143768 37 GlinertA.TurjemanS.ElliottE.KorenO

You should feel revitalized, refreshed, and hydrated

This is likely due to collagen having a VERY low leucine content & leucine is the amino acid responsible for stimulating muscle protein synthesis Perhaps collagen has benefits but I will want to see a much more fleshed out mechanism & more hard objective outcome data before I recommend it as a supplement

This product is not a drug, food, or cosmetic and may not be misbranded, misused, or mislabeled as a drug, food, or cosmetic

de Gooijer MC, de Vries NA, Buckle T, Buil LCM, Beijnen JH, Boogerd W, van Tellingen O