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MAA occurs in a highly reproducible pattern, preferentially affecting the temples, vertex and mid frontal scalp

Proof of principle for this approach was obtained in a mouse model of breast cancer where autotaxin inhibition decreased ARE activation and the consequent expression of anti-oxidant proteins and MDRT 49

SS-31 has Phase 2 and Phase 3 trials across multiple indications, FDA approval in Barth syndrome (as Forzinity), and a pharmaceutical company (Stealth BioTherapeutics) running a full development pipeline behind it

Uysal, H

With Finasteride or Dutasteride DHT blockers address the hormonal component of androgenetic alopecia

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