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During clinical trials, QTc prolongation emerged as the primary dose-limiting adverse event, but was reported to be manageable [6]

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To compare symptoms as categorical variables, we used the 2 test or Yatess continuity correction between two groups and the McNemar test within groups pre and postintervention

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DOI:10.1111/j.1749-6632.2002.tb04690.x [ Links ] 9