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Martin, E., Zhang, A., & Campiche, R

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In addition to MNAM and NNMTi, three new NAM analog inhibitors were reported for the treatment of MetS-related disorders in animal models: JBSNF-000088 ( JBSNF-000265 (Ruf et al., 2018), and JBSNF-000028 (Ruf et al., 2022)

The integration of finite element modeling, cadaveric studies, advanced imaging techniques, and biophysical analyses, including molecular biophysics, offers a comprehensive understanding of how these forces contribute to ligament failure