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Because of this dual role, MOTS-c is often described as a mitokine a mitochondrial-derived signaling molecule that influences cells throughout the body

Protein surveillance machinery in brains with spinocerebellar ataxia type 3: redistribution and differential recruitment of 26S proteasome subunits and chaperones to neuronal intranuclear inclusions

However, current knowledge still falls short of arriving at a relative unanimous panel of diagnostic miRNAs for clinical application

In clinical trials, GLP-1 receptor agonists have demonstrated substantial and clinically meaningful weight loss

In BMDMs, DRP1 knockdown initiated NLRP3 inflammasomal activation and IL-1 secretion, while inducing mitochondrial fission attenuated NLRP3 inflammasomal assembly and activation (165)
