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44 Arginine is suggested as a potential biomarker in hepatic and renal injuries and served as a precursor for BUN and Cr

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In the intestine and liver, curcumin is readily conjugated to form curcumin glucuronide and curcumin sulfate or, alternately, reduced to tetrahydrocurcumin, hexahydrocurcumin, and octahydrocurcumin ( Figure 2 ) (4)

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