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Articular cartilage is a complex and specialized tissue that provides a slick and bouncy cushion between bones at the joints

acnes gene-expression pattern also changed, the researchers found

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Mechanistically, YAP/TAZ induce the expression of SLC7A11 in a TEAD-dependent manner, and sustain the protein stability, nuclear localization, and transcriptional activity of ATF4 which in turn cooperates to induce SLC7A11 expression

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2014;9 doi: 10.1371/journal.pone.0109818