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Joint & Muscle Health Support (1,500mg) Here, the blend consists of a single ingredient: methylsulfonylmethane (MSM) , a naturally occurring sulfur compound that can reduce inflammation, joint pain, and muscle pain.54 The standard MSM dose is 1.56.0g per day, so IM8 gives us a good amount.55 (By the way, MSM appears to be effective at reducing the visible signs of skin aging, too).56 Heart Health Support (100mg) Again we have a single-ingredient blend. This time, the ingredient is coenzyme Q10 (CoQ10) , an antioxidant with clinically demonstrated cardiovascular health benefits

irAEs, immune-related adverse events

doi: 10.1016/s0140-6736(25)00553-7 304 PanJ.HuC.YuJ

It reduces the levels of metabolites including leukotriene B4 and prostaglandin E2, alters the serum metabolic profile, modulates lipid metabolism-related pathways, and thereby alleviates hypertension-induced renal injury [173]

Proc Nat Acad Sci USA 103:1301013015 Gray SB, Brady SM (2016) Plant developmental responses to climate change

Basic Res Cardiol (2016) 111:26